10 results
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
cardiac muscle, RBC, Kidney ... Cardiac muscle, Kidneys ... intestines, White blood cells ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Liver Injury - Differential ... disease - If ALP ... both are normal, ALP ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Chemistry Tests - AST, ALT ... Metabolism AST and ALT ... cardiac muscle > kidney ... cytoplasmic (CAST) • ALT ... #Pathophysiology
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
tubule of the kidney ... adult population: also ... collection with EDTA Pathophysiology ... respiratory failure • Neurologic ... Hyophosphatasia #hepatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
lymphocyte predominant (LP ... B symptoms not as ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... ) Summary ALS: combination ... lateral sclerosis Pathophysiology ... conditions listed in differential ... Lateral #Sclerosis #neurology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... ATRA treatment Pathophysiology ... Release from blast cells ... initiation • Differential ... diagnosis #management #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... 5X ULN • AST/ALT ... AST declines > ALT ... nephrotoxicity to kidney ... tubular cells
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... abnormal under the microscope ... abnormal under a microscope ... blood count with differential ... Syndromes #diagnosis #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
affects the skin, neurologic ... musculoskeletal systems • Kidneys ... (PR3-ANCA)): Microscopic ... , Elevated AST ALT ... aneurysms can also