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antiarrhythmics cardiology classes table adrenergic adrenoceptor anaphylaxis comparison diagnosis drugs hypersensitivity hypersensitivityreaction immunosuppressant management phases reactions treatments type2 types vaughan
Immune Reactions and Immunosuppressant Drugs Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2 Muromonab-CD3 - Monoclonal antibody Calcineurin
Immune Reactions ... Basiliximab - IL-2 receptor ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology ... #immunology
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
via their Fc receptor ... When the specific allergen ... Hypersensitivity #Types #Classification ... #Pathophysiology ... #Reactions #Table
Antiarrhythmics - Vaughan Williams Classification Class I (Ia, Ib, Ic) - Na+ Channel Blockade • Slows depolarization
Vaughan Williams Classification ... Class II - Beta Receptor ... Blockade • Prolongs action ... VaughanWilliams #Classification ... Classes #cardiology #pharmacology
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
Antigen binds receptor ... foreign -> B-cells ... the cell surface receptor ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Anaphylaxis: Treatments (Acute) Additional Info: • IV steroids may be considered for prevention of late phase reactions.
of late phase reactions ... provided, as well as allergy ... • H2 receptor ... Treatments #Management #pathophysiology ... #immunology
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... beta adrenergic receptors ... ++ influx into cells ... Vaughan #Williams #Pharmacology ... #Classes #pathophysiology
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... Vaughan Williams Classification ... beta adrenergic receptors ... #Classification ... #Classes #pathophysiology
Adrenoceptor Actions α1 • Vascular smooth muscle - Contraction • Genitourinary smooth muscle - Contraction • Intestinal
Adrenoceptor Actions ... • Pancreatic ß-cells ... Adrenoceptor #adrenergic #receptors ... #actions #pharmacology ... #pathophysiology
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