11 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... decr release and activity ... Manifestations #pathophysiology ... #diagnosis #signs ... #symptoms #complications
An Algorithm for the Management of Seizures

The management of active seizures is algorithmic, starting with a
Algorithm for the Management ... of active seizures ... and bag-valve mask ... continuous vital sign ... Pharmacologic treatment
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Excessive glutamate activity ... of UMN and LMN signs ... by decreasing activity ... neurology #diagnosis #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... macrophages and T cells ... Langerhans giant cells ... • GU system Complications ... TB #Diagnosis #Management
Pediatric Trauma Primary Survey: C-ABCDE
C - Catastrophic Bleeding - Life-threatening hemorrhage
 • Apply direct pressure/compression bandage
Pediatric Trauma ... • If active bleeding ... need For blood, activate ... cord injury #Pediatrics ... Survey #CABCDE #management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... macrophages and T cells ... Langerhans giant cells ... • GU system Complications ... TB #Diagnosis #Management
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
clinical findings and complications ... Incr Sympathetic Activity ... BZD #withdrawal #pharmacology ... #pathophysiology ... #diagnosis #signs
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... increased B-cell activity ... anterior/posterior MSK ... #Signs #Symptoms
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... monophasic Pathophysiology ... • Bilateral signs ... Pleocytosis > 100 cells ... Myelitis #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
, B cells, and plasma ... phenomenon (16%) MSK ... lubricants • Pharmacologic ... muscarinic agonists • Active ... Rheumatology #Diagnosis #Management