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diagnosis neurology dermatology acquired als amyotrophic causes damage differentiation encephalopathy exposure immune inflammatory iris lateral leukostasis lysis myelitis oncology posterior
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Release from blast cells ... initiation • Differential ... #management #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... adsorption onto cancer cells ... #treatment #hematology ... #differential
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
- MRI: inflammation ... , breast bone, pelvis ... antiinflammatory properties e.g ... diagnosis #management ... #Dermatology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... of diagnosis (e.g ... anterior/posterior MSK
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Etiology: • Pathophysiology ... Vascular narrowing on MRA ... Reversible course Differential ... • EEG: With persistent ... #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... cord compression (MRI ... Pleocytosis > 100 cells ... Myelitis #diagnosis #management ... #neurology #differential
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... EMG: LMN Signs in ... MRI: Brain, cervical ... conditions listed in differential ... neurology #diagnosis #management
A quick infographic on the importance of sun protection and the various results of sun damage
Toxicol Appl Pharmacol ... Geller AC, Heneghan MK ... Welsh MM, Karagas MR ... Dong K, Goyarts EC ... damage in skin cells
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... increase in CD4+ cells ... #Inflammatory #Syndrome ... #Differential # ... Diagnosis #Management
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