16 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
and Symptoms Anaphylaxis ... : when any egg of ... Neurological Compromise (e.g ... Cardiac Compromise (e.g ... #pathophysiology
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
Lipid mediators (e.g ... Other mediators (e.g ... inflammatory mediators (e.g ... #pathophysiology ... #immunology
Approach to ECGs - Tachy/Bradyarrhythmias
Tachyarrhythmias - HR > 100
Wide
  (1) VT - DANGER
  (2)
(2) Sick Sinus Syndrome ... bradyarrhythmia #ECG ... #EKG #diagnosis ... electrocardiogram #cardiology ... #differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
from precursor cells ... immunity Signs/Symptoms ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Prednisone 5mg/kg ... Diagnosis: >3 symptoms ... initiation • Differential ... PE, DAH, CHF, Anaphylaxis
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
or plasma cells ... storage sites (e.g ... proliferate and differentiate ... Humoral #Immunity #pathophysiology ... #immunology
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
(e.g., long QT ... syndrome, ARVC) ... Digoxin toxicity Symptoms ... 300 = NSVT EKG ... #cardiology
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Pulmonary Edema - Differential ... Framework NCPE Pathophysiology ... level <100 pg/ml EKG ... respiratory distress syndrome ... #diagnosis #cardiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... of diagnosis (e.g ... : (distinct symptoms ... ) • Löfgren syndrome