22 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... Prednisone 5mg/kg ... Diagnosis: >3 symptoms ... initiation • Differential ... #management #hematology
Irritable Bowel Syndrome (IBS) - Pathophysiology, Diagnosis and Management Algorithm
Risk factors: Previous acute enteric infection, Female
(IBS) - Pathophysiology ... Diagnosis and Management ... (e.g. fibromyalgia ... factors affecting symptom ... #Pathophysiology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... treatment #hematology #differential
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... : • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG ... TLS #diagnosis #management
Approach to ECGs - Tachy/Bradyarrhythmias
Tachyarrhythmias - HR > 100
Wide
  (1) VT - DANGER
  (2)
(2) Sick Sinus Syndrome ... bradyarrhythmia #ECG ... #EKG #diagnosis ... electrocardiogram #cardiology ... #differential
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
from precursor cells ... immunity Signs/Symptoms ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Humoral Immunity - Pathogenesis and Clinical Findings
Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
or plasma cells ... storage sites (e.g ... proliferate and differentiate ... Humoral #Immunity #pathophysiology ... #immunology
Premature Ventricular Complexes (PVC's) - Summary Framework

Why PVCs?  Can be the first manifestation of cardiac
(e.g., long QT ... syndrome, ARVC) ... Digoxin toxicity Symptoms ... 300 = NSVT EKG ... #cardiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... of diagnosis (e.g ... Sarcoidosis #Diagnosis #Management
Noncardiogenic Pulmonary Edema - Differential Diagnosis Framework

NCPE Pathophysiology:
Noncardiogenic pulmonary edema occurs because of excessive pulmonary capillary
Pulmonary Edema - Differential ... Framework NCPE Pathophysiology ... level <100 pg/ml EKG ... respiratory distress syndrome ... #diagnosis #cardiology