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diagnosis management headache hematology signs syndromes agammaglobulinemia aids algorithm als amyotrophic associated barre bee bradyarrhythmia bradycardia complexes cord dementia differentiation
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Prednisone 5mg/kg ... Diagnosis: >3 symptoms ... initiation • Differential
Approach to ECGs - Tachy/Bradyarrhythmias Tachyarrhythmias - HR > 100 Wide (1) VT - DANGER (2)
(2) Sick Sinus Syndrome ... bradyarrhythmia #ECG ... #EKG #diagnosis ... electrocardiogram #cardiology ... #differential
Approach to Headaches - Differential Diagnosis Algorithm Red flags (PHANTOMS): • Pattern change, progressively worse, papilledema •
papilledema • Horner syndrome ... ) • Systemic symptoms ... and signs (e.g. ... CNS infection (e.g ... Diagnosis #Algorithm #neurology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings The epidemiology of this disease is 1/340,000 births and roughly double
from precursor cells ... immunity Signs/Symptoms ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
BEE Syndromes - Non-inflammatory Causes Immune-mediated conditions affecting the Brain, Eye, and Ear Visual or auditory symptoms in
Visual or auditory symptoms ... conjunction with symptoms ... skull neoplasms (e.g ... #neurology #noninflammatory ... #differential #
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
or plasma cells ... storage sites (e.g ... proliferate and differentiate ... Humoral #Immunity #pathophysiology ... #immunology
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
(e.g., long QT ... syndrome, ARVC) ... Digoxin toxicity Symptoms ... 300 = NSVT EKG ... #cardiology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... • EEG: With persistent
HIV-Associated Neurocognitive Disorder (HAND) Definition: HIV-Associated Neurocognitive disorders categories: • Asymptomatic neurocognitive impairment • Mild neurocognitive impairment • HIV dementia Pathophysiology: HIV frequently
HIV dementia Pathophysiology ... CNS ○ Infected cells ... • Depressive symptoms ... The clinical syndrome ... dementia #AIDS #Neurology
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