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diagnosis management neurology hematology algorithm causes guillain acidosis acquired als amyotrophic apml atrophicglossitis bradyarrhythmia bradycardia candida chf classification clinical complexes
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... Pathophysiology ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis ... #management #treatment
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
Short Stature - Differential ... • Turner Syndrome ... Panhypopituitarism Treatment ... Metabolism Error • Immunologic ... #ShortStature #Differential
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... adsorption onto cancer cells ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Guillain-Barré Syndrome (GBS) Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness Epidemiology: • Incidence: 1
Guillain-Barré Syndrome ... Electrodiagnostic studies (Ex EMG ... the underlying pathophysiology ... and cauda equina TREATMENT ... #Syndrome #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... organ damage • Treatment ... : • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... life-threatening Differential ... Serologic and EMG ... first step in immunologic
Approach to ECGs - Tachy/Bradyarrhythmias Tachyarrhythmias - HR > 100 Wide (1) VT - DANGER (2)
Approach to ECGs ... (2) Sick Sinus Syndrome ... block (lower AV cells ... electrocardiogram #cardiology ... #differential
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
or plasma cells ... storage sites (e.g ... proliferate and differentiate ... Humoral #Immunity #pathophysiology ... #immunology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Pathophysiology ... Release from blast cells ... initiation • Differential
Tongue Pathology Geographic tongue, fissured tongue, and hairy tongue are the most common tongue problems and
do not require treatment ... by the Epstein-Barr ... require biopsy to differentiate ... benign lesions (e.g ... Burning mouth syndrome
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