6 results
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
and Symptoms Anaphylaxis ... : when any egg of ... Neurological Compromise (e.g ... Cardiac Compromise (e.g ... #pathophysiology
Anaphylaxis: Pathogenesis
Anaphylaxis is a Type 1 hypersensitivity reaction
While the primary mechanism of anaphylaxis is mast cell
Lipid mediators (e.g ... Other mediators (e.g ... inflammatory mediators (e.g ... #pathophysiology ... #immunology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... : • Pathophysiology ... Lysis of tumor cells ... unless worrisome EKG
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
from precursor cells ... immunity Signs/Symptoms ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology ... #immunology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Prednisone 5mg/kg ... Diagnosis: >3 symptoms ... PE, DAH, CHF, Anaphylaxis
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... tissue: Epithelioid cells ... of diagnosis (e.g ... : (distinct symptoms ... ) • Löfgren syndrome