33 results
Coagulation Cascade and Anticoagulant Sites of Action

- Amy Chung, MD, MSc https://twitter.com/AmyChung

#AntiCoagulation #Cascade #Anticoagulants #Medications #Pharmacology
#Medications #Pharmacology ... #Pathophysiology ... Mechanisms #DOAC #Hematology
Dysmorphic Red Blood Cells on Electron Microscopy
This eyeSCANdy image shows dysmorphic red blood cells from the
Dysmorphic Red Blood Cells ... on Electron Microscopy ... dysmorphic red blood cells ... clinical #pathology #hematology
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
Sezary #Syndrome #Cells ... Pathology #Smear #Microscopy ... #Hematology
Peripheral Blood Smear Analysis
Hypochromia
Megaloblastic Anemia
Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS)
Microspherocytes: Autoimmune hemolytic anemia
Sickled red
anemia Sickled red cells ... disease Bite cells ... Smear #Analysis #hematology ... #microscopy #interpretation
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
in Cirrhosis • Pathophysiology ... BetaBlockers #Cirrhosis #hepatology ... #management #pharmacology
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... Cytokines, Mast Cells ... perivascular inflammatory cells ... Vasculitis #HUV #Pathophysiology ... #Rheumatology
Lactulose: Mechanism of Action in Hepatic Encephalopathy
Lactulose → ↑ Lactic Acid, Acetic Acid → ↓ pH
#Lactulose #pharmacology ... mechanism #ammonia #hepatology ... #pathophysiology
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
gout #uricacid #pathophysiology ... #pharmacology # ... rheumatology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Pathophysiology: ... germinative skin cells ... Skin-homing T-cells ... #Diagnosis #Dermatology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
polychromatophilic cells ... hemolytic #anemia #Hematology ... Pathology #Smear #Microscopy