16 results
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 • MOA: Block fast Na+ channels
repolarization CLASS 3 - Potassium ... ++ influx into cells ... Vaughan #Williams #Pharmacology ... Classification #Classes #pathophysiology ... #cardiology
EKG CHANGES AS A RESULT OF CHANGES IN NA OR K CHANNEL CONDUCTION - GRAPHIC BY
EKG CHANGES AS A ... RESULT OF CHANGES ... JAMES LI, MD #Pathophysiology ... #Toxicology #Cardiology ... #NaK #Sodium #Potassium
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
Antiarrhythmics Pharmacology ... repolarization CLASS 3 - Potassium ... inotropy) ACCP Cardiology ... Classification #Classes #pathophysiology ... #phases #cardiology
Drugs affecting the cardiac action potential. The sharp rise in voltage ("0") corresponds to the influx
to the sodium-channel ... repolarizing eflux of potassium ... voltage-sensitive calcium channels ... #Pathophys #Pharmacology ... #Cardiology #Antiarrhythmics
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... Decreased ENaC channel ... #Hyperkalemia #Pathophysiology ... #Pharmacology # ... Impaired #Potassium
Antiseizure Drugs 
Sodium Channel Blockers: Carbamazepine, Oxcarbazepine, Eslicarbazepine, Lamotrigine, Lacosamide, Phenytoin, fosphenytoin
Broad Spectrum: Valproate, Levetiracetam, Brivaracetam,
Drugs Sodium Channel ... Tiagabine, Vigabatrin Potassium ... Channel Opener: ... medications #epilepsy #pharmacology ... #comparison #table
Antiarrhythmics - Sodium Channel Blockers
Subclasses, Mechanisms, Indications, Side Effects
la - Quinidine, Procainamide
lb - Lidocaine, Mexiletine
Ic -
Antiarrhythmics - Sodium Channel ... Antiarrhythmics #Sodium #Channel ... Blockers #ClassI #Na #cardiology ... #pharmacology # ... table #comparison
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... ATP-sensitive potassium ... channel in pancreatic ... beta cells, triggering ... Sulfonylureas #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Heparin) • Sodium-channel ... differential #diagnosis #pathophysiology ... #pharmacology # ... potassium #medications
Calcium Channel Blockers - Dihydropyridines vs Non-Dihydropyridines
Dihydropyridines (amlodipine, felodipine, nifedipine, nicardipine)
 • SVR: Decrease
 • Inotropy:
Calcium Channel ... CCBs #Calcium #Channel ... NonDihydropyridines #pharmacology ... #comparison #table ... #cardiology