11 results
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Constitutional Syndromes ... #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... = funny-shaped cells ... old, ~10,000 new cases ... treatment #hematology #oncology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
- Differential Diagnosis ... Hyperviscosity Syndrome ... neutrophil count < 500 cells ... : Tumor Lysis Syndrome ... #differential #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... • Anemia • Aplastic ... #diagnosis #hematology ... #oncology
Causes of Gallbladder Wall Thickening - Differential Diagnosis
 • Physiologic: Contracted gall bladder in a non-fasting
Causes of Gallbladder ... - Differential Diagnosis ... cirrhosis, Nephrotic syndrome ... #Differential #Diagnosis ... #radiology #POCUS
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... Pure red cell aplasia ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology ... #Diagnosis
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... e.g., uptake by cells ... / hypoxemia -> focus ... laboratory or diagnostic ... - Compartment syndrome
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... Acquired - Aplastic ... Purpura #Bruising #Causes ... #peds #pediatrics ... #diagnosis #differential
Approach to ECGs - Tachy/Bradyarrhythmias
Tachyarrhythmias - HR > 100
Wide
  (1) VT - DANGER
  (2)
(2) Sick Sinus Syndrome ... 200ms from longer pause ... block (lower AV cells ... bradyarrhythmia #ECG #EKG #diagnosis ... electrocardiogram #cardiology