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differential hematology management mds myelodysplastic acidosis anemia bradyarrhythmia bradycardia bruising classification ecg electrocardiogram elevation lactate lactic myelodysplasia pediatrics purpura syndromes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Constitutional Syndromes ... #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... = funny-shaped cells ... old, ~10,000 new cases ... treatment #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... • Anemia • Aplastic ... #diagnosis #hematology ... #oncology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... Acquired - Aplastic ... Purpura #Bruising #Causes ... #peds #pediatrics ... #diagnosis #differential
Approach to ECGs - Tachy/Bradyarrhythmias Tachyarrhythmias - HR > 100 Wide (1) VT - DANGER (2)
(2) Sick Sinus Syndrome ... 200ms from longer pause ... block (lower AV cells ... #EKG #diagnosis ... electrocardiogram #cardiology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... ., uptake by cells ... / hypoxemia -> focus ... laboratory or diagnostic ... - Compartment syndrome
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