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diagnosis hematology chronic classification cll differential hemeonc leukemia lymphocytic mds myelodysplastic acidosis algorithm aplastic apml causes differentiation elevation foamed hemophagocytic
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... cytopenias (usually anemia ... #treatment #hematology ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... Treatment: ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... factor (GCSF) treatments ... marrow studies Treatment ... Immunosuppressive treatment ... diagnosis #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
lymphocytes, smudge cells ... 5) Symptoms of anemia ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... hemeonc #diagnosis #management
Tumor Lysis Syndrome An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... malignancies Treatments ... Walid Malki, MD, MS ... #TLS #oncology ... #management #UricAcid
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Release from blast cells ... APML #diagnosis #management ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Hodgkin Lymphoma Treatment ... classification #hematology #oncology ... #management
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
which all carry treatment ... In both SK and AK ... for Refeeding Syndrome ... differential #algorithm #management ... #treatment #criticalcare
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
e.g., uptake by cells ... / hypoxemia -> focus ... before beginning treatment ... - Compartment syndrome ... 30mmHg) - Severe anemia
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