17 results
diagnosis symptoms rheumatology differential hemophagocytic hlh lymphohistiocytosis neurology syndrome treatment als amyotrophic arteritis bullous centralretinalartery coagulation complications crao dermatology diabetes
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings Medical Comorbidities Malignancies (most commonly hairy-cell leukemia) Immunogenetic Predisposition: patient is
Viral replication causes ... vascular endothelial cells ... PolyarteritisNodosa #Pathophysiology ... #Diagnosis #Signs ... #Symptoms #Vasculitis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... various inflammatory cells ... periumbilical region), nausea ... HenochScholeinPurpura #Pathophysiology ... #Diagnosis #Signs
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
• Langerhan cells ... hair follicles -> causes ... Livedo Reticularis, Vasculitis ... Manifestations #pathophysiology ... #diagnosis #signs
Bullous Pemphigoid - Diagnosis and Management Summary Pathophysiology: Autoantibody-mediated damage to epithelial basement membrane -> separation of
Diagnosis and Management ... Summary Pathophysiology ... dermis Clinical Signs ... - Erosions and crusts ... #dermatology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
diffusion of K+ out of cells ... may cause serum ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... Lysis of tumor cells ... TLS #diagnosis #management ... #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... Multinucleated giant cells ... tract, and often causes ... Differential #Diagnosis #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... Drugs, Unknown cause ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... of UMN and LMN signs ... Escorial criteria uses ... neurology #diagnosis #management
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
anti-coagulation • Hematologic ... retinal edema caused ... Retina • Ganglion cells ... Occlusion #CRAO #pathophysiology ... ophthalmology #diagnosis #signs
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