16 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
second hit' -> Malignant ... mutated in all cells ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms
Diagnostic Algorithm for Suspected Pulmonary Embolism

Well's Criteria for PE
 • Clinical Signs and Symptoms of DVT
Diagnostic Algorithm ... Pulmonary Embolism Well's ... PE • Clinical Signs ... and Symptoms of ... Hemoptysis - 1.0 • Malignancy
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Disorders Testing Algorithm ... workup for specific symptoms ... for secondary causes ... organ-specific signs ... or symptoms (eg
Management of patients with known or suspected malignant pleural effusion (MPE) - An Official ATS/STS/STR Clinical
known or suspected malignant ... there are any signs ... /symptoms of worsening ... #Malignant #Pleural ... Effusions #MPE #Algorithm
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Is visual loss caused ... the optic nerve caused ... Doppler US : halo sign ... #Rheumatology #Ophthalmology ... #Diagnosis #Algorithm
Polyarteritis Nodosa (PAN): Pathogenesis and Clinical Findings

Medical Comorbidities Malignancies (most commonly hairy-cell leukemia)
Immunogenetic Predisposition: patient is
Viral replication causes ... vascular endothelial cells ... necrotic purpura - Malignant ... Pathophysiology #Diagnosis #Signs ... #Symptoms #Vasculitis
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings

Ophthalmic Artery Hypertension
Stage 1: Mild/vasoconstrictive
 • Acute and chronic vasospasm
hyalinization causes ... Spots Stage 4: Malignant ... pathophysiology #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
diffusion of K+ out of cells ... may cause serum ... Signs/Symptoms/Complications ... Abdominal pain, nausea ... pathophysiology #endocrinology
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
the mastoid air cells ... hearing loss, nausea ... pathophysiology #signs ... #symptoms #diagnosis ... #otology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hematological malignancy ... of about three cases ... ingestion • B symptoms ... Lymphoma (90-95% of cases ... classification #hematology #oncology