11 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... paraneoplastic sign ... #LeserTrelat #Sign ... #PhysicalExam # ... #oncology
Iridodonesis

Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
movement, is a sign ... characteristic sign ... with Marfan’s syndrome ... #Video #Ophthalmology ... #Signs #Ocular
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's Sign ... Nikolsky's sign ... #TEN #Dermatology ... #PhysicalExam # ... Video #Clinical
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... Myelodysplastic syndromes ... blood count with differential ... #diagnosis #hematology ... #oncology
Iridodonesis

Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
movement, is a sign ... characteristic sign ... with Marfan’s syndrome ... #Video #Ophthalmology ... #Signs #Ocular
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Release from blast cells ... • Induce blast cell ... initiation • Differential ... #oncology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome ... Episcleritis Signs ... general feeling of ill ... #diagnosis #dermatology ... #oncology
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
consciousness Differential ... • Locked-in syndrome ... stimulation to all ... • Examine for signs ... caseyalbin #PhysicalExam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... purpura: Strong sign ... CRP GCA (Giant Cell ... Multinucleated giant cells