Lellis treatment hematology ucsdh vasculitis anemia clinical purpura dermatology syndrome

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Vasculitis: In this instance, idiopathic with palpable purpura.

Charlie Goldberg, M.D. - UCSD Catalog of Clinical Images

#Clinical

Vasculitis: In this ... with palpable purpura ... Images #Clinical ... #Photo #Dermatology ... #UCSDH

Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage

- Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology

Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and

Dermatologic Manifestations ... Rarely dominate the clinical ... • Goodpasture syndrome ... #Dermatologic ... Polyangiitis #GPA #dermatology

Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... Rheumatologic, Vasculitides ... Diagnosis #Algorithm #hematology

VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
• Common Clinical Features: alveolitis, ear and

Clinical Syndrome ... : • Common Clinical ... recurrent fevers, vasculitis ... Abnormalities: macrocytic anemia ... criteria for 1) hematologic

Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells

Myelodysplastic Syndrome ... = funny-shaped cells ... cytopenias (usually anemia ... only curative treatment ... #hematology #oncology

Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years

What?
• Aplastic anemia

Constitutional Syndromes ... Clinical Presentation ... Constitutional Syndromes ... Treatment: ... #oncology #hematology

Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment

(HSP, IgA Vasculitis ... on tuberculosis treatment ... Schonlein #HSP #IgA #Vasculitis ... #clinical #photo ... #dermatology #skin

Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of

Clinical Presentation ... (Petechial or purpuric ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology

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