14 results
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... , Vasculitis, Purpura ... ) Blood (75%): Anemia
Palpable Purpura seen in Henoch Schonlein Purpura (HSP, IgA Vasculitis)

55 year old male on tuberculosis treatment
(HSP, IgA Vasculitis ... on tuberculosis treatment ... #clinical #photo ... #dermatology #skin ... #rash #physicalexam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Presentation: Systemic Symptoms ... Multinucleated giant cells ... , mucositis • Rash ... • Progressive symptoms ... Differential #Diagnosis #Rheumatology
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
Bandemia, AKI. ... +purpuric rash → ... purpura fulminans ... #Rash #dermatology ... #clinical #photo
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... Treatment: ... • Improve the symptoms ... #oncology #hematology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
integrity of: • Skin ... poor nutrition Clinical ... Psychiatric symptoms ... Loss of teeth Anemia ... Treatment:
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... immunophenotype Clinical ... marrow failure with anemia ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Leukocytoclastic vasculitis ... Treatment: - Systemic ... #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... lesions, palpable purpura ... Behcet syndrome (Clinical ... Arthritis, AS Treatment ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Hepatomegaly • Skin ... • Neutropenia, anemia ... #hematology