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management differential rheumatology leukemia monoclonal syndrome algorithm anemia chronic cll comparison dermatology hemeonc hemolytic table acute agglutinin biliary cell cholangitis
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... , smudge cells are ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #hematology #hemeonc
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
can indicate disease ... microglobulin Treatment ... #Leukemia #diagnosis ... #workup #oncology ... #hematology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... No necrosis, No vasculitis ... + cells" Treatment ... #phenotypes #workup ... #treatment #rheumatology
Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) IgM
Treatment of Non-hepatitis ... chloraminophene IgG ... Target plasma cells ... /or refractory disease ... #Management #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemia): • Lymphocytes ... extramedullary disease ... CLL (Chronic Lymphocytic ... #Leukemia #Hematology ... #Oncology #Diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... Rebound effect from treatment ... Rheumatologic, Vasculitides ... , IBD, Celiac disease
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle cells ... cardiac valve, vasculitis ... #Algorithm #workup ... #hematology #testing
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
glands: • Focal lymphocytic ... UIP, NSIP): • Lymphocytic ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology: • T lymphocyte ... but elevated as disease ... group cholangitis, IgG4 ... related disease ... #workup #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma Workup ... number of sites of disease ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
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