45 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
drug reaction, infection ... glucocorticoid treatment ... organ-specific signs ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
., HIV), EBV infection ... Etiology: - Infections ... Diagnosis of B-Symptoms ... #differential # ... hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... : HLH signs and ... can mimic common infections ... : • Infection ... #hematology
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
vasculitis (3%) • Infections ... #semiology #signs ... #lesions #diagnosis ... #clinical #manifestations ... pathology #lesions #differential
Causes of Priapism
Many disease states have been associated with priapism, including hematologic disorders, malignancy, neurologic disorders,
priapism, including hematologic ... disorders, malignancy, neurologic ... disorders, trauma, infection ... #Causes #Differential ... #Table
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
HIV / AIDS - Differential ... Diagnosis Framework ... should be based on clinical ... Antimicrobial treatment ... #differential #
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... test - Cogan sign ... - Peek sign ... precipitated by: Drugs, infection ... #management #neurology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Infectious: Mycoplasma ... #management #treatment ... #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Clinical Presentation ... younger pts) Differential ... sensitize red blood cells ... hemolytic #anemia #hematology ... #diagnosis