12 results
THE LIMPING OR NON-WEIGHT BEARING CHILD PATHWAY

RED FLAGS - In all cases there are specific
markers which
RED FLAGS - In all ... suspicion of severe disease ... splenomegaly, abnormal neurology ... Rheumatology ... #Child #Peds #Pediatrics
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... (for secondary APS ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... and diplopia) • Vascular ... Medium and large also ... Syndrome #diagnosis #management ... signs #symptoms #rheumatology
Diagnosis of IgA Vasculitis (Henoch-Schönlein Purpura) - French Vasculitis Study Group 

1) Suggestive clinical manifestations
- Systemic disease ... post-capillary venules and also ... the skin, with vascular ... HSP #Diagnosis #Rheumatology ... #Peds #Pediatrics
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
, breast bone, pelvis ... osteoarticular and skin disease ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Presentation: - Disease ... course of the disease ... 4) progressive muscular ... Lateral #Sclerosis #neurology ... #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Release from blast cells ... Cathepsin G release → vascular ... unless severe APLS ... APML #diagnosis #management ... #hematology #oncology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulse deficits vascular ... Multinucleated giant cells ... affects the skin, neurologic ... cognitive impairment, neurologic ... Differential #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... number of sites of disease ... scans and can also ... classification #hematology ... #oncology #management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Presents as dyspnea ... potassium from lysed cells ... Borrellia (Lyme disease ... Transfusion #diagnosis #management ... #hematology #reactions