12 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
and Management ... = funny-shaped cells ... risk-stratification • Risks: infection ... #Management #treatment ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... Phagocytosis of blood cells ... Auto-amplification loop Diagnosis ... #management #treatment ... #summary #rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
hematopoietic stem cells ... number of CD34+ cells ... number of CD34+ cells ... Number of CD34+ cells ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
from mature B cells ... Reed-Sternberg cells ... History of EBV infection ... classification #hematology ... #oncology #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Release from blast cells ... opacities • Diagnosis ... • Differential Diagnosis ... : Infection (sepsis ... #management #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
lymphocytes, smudge cells ... Complications: 1) Infection ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
aggregate foci (>50 cells ... aggregate) of CD4 T cells ... , B cells, and plasma ... cells around salivary ... #Diagnosis #Management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
potassium from lysed cells ... Infection - Infection ... likely to cause infections ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
potassium from lysed cells ... • Infection - ... Infection occurs ... #Transfusions #diagnosis ... #management #hematology
IDSA Recommendations for Preventing and Treating Varicella Zoster Virus (VZV) Infections in HIV-AIDS
Pre-Exposure Prevention of VZV
of VZV Primary Infection ... CD4 count ≥200 cells ... health-care provider diagnosis ... Prevention #Treatment #management ... #HIVAIDS #pharmacology