28 results
diagnosis hematology treatment disease oncology syndrome stills adultonset anemia aosd aplastic blood dermatology hemophagocytic hlh lymphohistiocytosis product reactions summary 2ndline
Leser–Trélat Sign on Physical Exam Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy. #Leser
Leser–Trélat Sign ... #Leser #Trélat # ... Trelat #LeserTrelat
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 Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Periodic fever ... - Nonremitting fever ... ALT ↑ bilirubin level ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
Dermatomyositis • Fever ... disease and ILD • Liver ... Liver biopsies show ... Abs, and to a lesser ... Dermatomyositis #rheumatology
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
- Fever spikes ... Fever of at least ... /splenomegaly, liver ... AOSD #diagnosis #rheumatology ... #management
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
if neutropenic fever ... Anemia #diagnosis #management ... #treatment #hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Disease #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... Systemic AOSD: high fever ... Disease #AOSD #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... , ↓ Fibrinogen level ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disease • Liver ... Low serum IgG level ... and M panel Management ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... lymph node, or liver ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
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