9 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... #Leser #Trélat # ... Trelat #LeserTrelat
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
- Virtually never ... Thrombocytopenia) and Hepatic toxicity ... monitored to reduce toxicity ... #Pharmacology #Antibiotics
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Therapeutic Drug Level ... at anytime if toxicity ... Sample trough level ... Ranges #Toxicology #Pharmacology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
metabolized in the liver ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
tool to assess level ... bradycardia. renal/liver ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... Renal failure, Liver ... #Colchicine #Toxicity ... Toxicology #Phases #Pharmacology
Lithium Therapy for Bipolar Disorder 
Toxicity Levels: 
 - Mild (1-1.5 mEq/L) 
 - Moderate (1.6-2.5
Bipolar Disorder Toxicity ... , weight gain Toxicity ... a target serum level ... order a lithium level ... #Pharmacology #
Digoxin Pharmacology and Monitoring

 • Digoxin’s half-life is 30-45 hours in healthy adults
 • When monitoring
Digoxin Pharmacology ... elevated digoxin level ... - Any level ... Kat_Watson #Digoxin #Pharmacology ... toxicology #management #toxicity
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
the serum MTX level ... evidence of marrow toxicity ... even if the MTX level ... Antidote #Toxicology #Toxicity ... #Management #Pharmacology