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diagnosis differential management causes common cvid erythematosus extravascular hemolysis hodgkins hypogammaglobulinemia immunodeficiency immunology intravascular lupus lymphoma macrocytic mentzerindex microcytic oncology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
infiltration (e.g. cancer ... Microangiopathic hemolytic ... defects (e.g. sickle cell ... #hematology #anemia ... differential #diagnosis #calculation
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... • Sickle cell ... within circulation ... anemia • ... #Causes #Hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... acute blood loss, hemolysis ... OR reticulocyte index ... #Workup #Hematology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... released into circulation ... are removed from circulation ... Pancytopenia is a hematologic ... indicates IDA Mentzer index
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Lymphoma or other cancers ... and autoimmune hemolytic ... anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Weight loss • Anemia ... nodosum • Immune hemolytic ... anemia • Pain ... #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... vein thrombosis Hematologic ... lymphopenia, low PLT • Anemia ... leukemia • Lung cancer ... • Cervical cancer
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