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diagnosis differential causes dermatology generalized lymphocytic management pruritus rheumatology secondary workup arthritis classification common cvid disease disorders erythematosus hemeonc hypogammaglobulinemia
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Reactive: - Systemic ... Age > 50 • Chronic ... #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... (Chronic Myeloid ... - infiltrates (anemia ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Scoring system: ... • Neutropenia, anemia ... leukemia #CLL ... #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Leukemia (CLL) ... 5) Symptoms of anemia ... #Leukemia #oncology ... #hematology #hemeonc
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Creatinine & BUN: • Chronic ... renal failure/uremia ... • Lymphoma • Leukemia ... #generalized #dermatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
site in lymphatic system ... with lymphatic system ... lymphadenopathy more diffuse ... Treated Like Acute Leukemias ... pathophysiology #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myelogenous Leukemia ... Leukemia • Idiopathic ... Syndromes #diagnosis #hematology ... #oncology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Creatinine & BUN: • Chronic ... renal failure/uremia ... • Lymphoma • Leukemia ... Pruritus #secondary #systemic ... #generalized #dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
pneumonitis • Diffuse ... enteropathy, and diffuse ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... Autoimmunity • Chronic ... autoimmune hemolytic anemia ... ) • Systemic granulomatous ... hypogammaglobulinemia #immunology #hematology
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