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diagnosis differential management causes arteritis chronic classification common cvid enlarged erythematosus gca giantcell hemolysis hodgkins hypogammaglobulinemia immunodeficiency immunology leukemia lupus
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Algorithm and Causes ... #Hemolytic #Anemia ... #Algorithm #Differential ... #Causes #Workup ... #Hematology #Diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Consider sickle cell ... valve, vasculitis, malignant ... #workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... concerning for malignancy ... for workup, including ... blood loss, Acute hemolysis ... , deficiency anemia
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Differential Diagnosis Algorithm ... Inflammatory • Systemic ... Serum Sickness Hemolytic ... Disease • Sickle Cell ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Scoring system: ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... corpuscular (cell ... acute blood loss, hemolysis ... #Workup #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Lymphoma (HCV) • CLL ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Giant cell arteritis ... particularly those coming ... vs infection vs malignancy ... complaints- anemia ... them, but urgent rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... and autoimmune hemolytic ... anemia) • Systemic ... Burns • Protein-losing ... hypogammaglobulinemia #immunology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
hematological malignancy ... nodosum • Immune hemolytic ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
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