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diagnosis differential pharmacology table binders binding cardiology classification comparison hypokalemia hyponatremia hypotonic k management medications pathophysiology physiologic treatment
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pathophysiology 1) ... works by directly ... intracellular calcium causes ... - Hyperkalemia ( ... high potassium levels
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... as necessary at 1- ... level teaspoons) 1- ... patients sensitive to high ... of aspiration #Potassium
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
: • Digoxin ... Increased K Intake: 1. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
: • Digoxin ... Increased K Intake: 1. ... differential #diagnosis #causes ... #potassium #high ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... +K / serum Na >1 ... diuresis can be high ... : Hypovolemia, Hypervolemia ... #nephrology
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... Digoxin and related ... Differential #Diagnosis #High ... #Potassium #Classification ... #Causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Calcineurin inhibitors, Digoxin ... reabsorption) Workup ... 5-10U reg IV + 1- ... Management #Treatment #potassium ... #nephrology #K
Pragmatic diagnostic algorithm for hypokalemia. ***Typical presentations: • Vomiting: urine Na/Cl > 1.6, low urine
Pragmatic diagnostic algorithm ... urine Na/Cl < 0.7, high ... with urine Na/Cl ~1. ... correcting serum potassium ... #nephrology
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