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diagnosis differential management pharmacology potassium treatment acute binding cardiology chronic comparison digoxin hypertension hyponatremia hypotonic medications pathophysiology physiologic screening secondary
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
also binds magnesium ... • Mechanism: Sodium-K ... nonspecifically binds ... #pharmacology #table ... #comparison #binders
Algorithm for Management of Acute and Chronic Hyperkalemia Acute Hyperkalemia: - IV calcium (10 mL of 10%)
Algorithm for Management ... in 4 mL) - IV sodium ... binders Chronic ... mL/min) - Oral sodium ... Chronic #treatment #nephrology
Digoxin Pharmacology and Pathophysiology 1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
Pump - Digoxin works ... intracellular calcium causes ... - Hyperkalemia ( ... Because digoxin binds ... , in states of hypokalemia
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Urine Na+K / serum ... : Hypovolemia, Hypervolemia ... differential #diagnosis #table ... #sodium #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Weakness, cramping, nausea ... reabsorption) Workup ... only if no clear cause ... Elimination (see Table ... Treatment #potassium #nephrology
Causes of Secondary Hypertension - Differential Diagnosis and Screening Testing Common causes: • Renal parenchymal disease
Causes of Secondary ... (correction of hypokalemia ... Oral sodium loading ... #Screening #Workup ... #table
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