14 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Algorithm for Differentiating ... Gitelman syndrome ... syndrome • Urine Chloride ... krithicism #Gitelman ... #nephrology #hypokalemia
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
salt-losing tubulopathies ... Family history of hypokalemia ... • Unexplained hypokalemia ... pressure Labs: • Hypokalemia ... pathophysiology #Hypokalemia
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Bartter syndrome, Gitelman ... @priti899 #Hypokalemia ... #causes #potassium ... #low #nephrology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
recessive salt-losing ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... Pathophysiology #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... evaluating hypokalemia ... in evaluating hypokalemia ... Bartter syndrome, Gitelman ... @krithicism #Hypokalemia
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... of hypokalemia ... Hypomagnesemia-induced hypokalemia ... Cushing's syndrome #hypokalemia ... #causes #nephrology
Causes of High-anion Gap and Non-anion Gap Metabolic Acidosis
Causes of High-anion Gap Acidosis:
 • Lactic acidosis
Hypokalemia ... Hyperkalemia ... Drug-induced hyperkalemia ... loads (ammonium chloride ... #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Algorithm Cl- ... Bartter syndrome, Gitelman ... the indicated causes ... #urine #Algorithm ... #nephrology #differential
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... Hypovolemia, UNa ... deficiency, Salt-losing ... tubal acidosis and metabolic ... #Causes #nephrology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Metabolic alkalosis ... NephTwitter) #Hypokalemia ... #Diagnosis #Causes ... #Workup #Nephrology