7 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Pathophysiology ... recessive salt-losing ... H+ secretion → Hypokalemia ... Metabolic alkalosis ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Low intake • Metabolic ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
salt-losing tubulopathies ... hypomagnesemia • Metabolic ... Hypochloremic metabolic ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... Pressure: - Metabolic ... Bartter syndrome, Gitelman ... Hippurate - Metabolic ... #diagnosis #Algorithm
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Differential Diagnosis Algorithm ... Hypovolemia, UNa ... deficiency, Salt-losing ... tubal acidosis and metabolic ... #Causes #nephrology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... - Bartter - Gitelman ... Differential #Diagnosis #Algorithm ... #Pathophysiology ... #Nephrology #Chloride
Classification of Diabetes Insipidus

Central or neurogenic diabetes insipidus:
 - Congenital - Structural malformations affecting the hypothalamus
Classification of ... mutations in the gene encoding ... Obstructive uropathy, Metabolic ... causes (e.g., hypokalemia ... #Types #Nephrology