5 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome Pathophysiology ... recessive salt-losing ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... #nephrology #diagnosis
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm

Reduced flow through distal nephron - TTKG
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... #IntercellularShift ... #Nephrology #Differential ... #Diagnosis #Algorithm
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
salt-losing tubulopathies ... alkalosis • Normal or low ... • Congenital chloride ... Syndrome #diagnosis #nephrology ... #management #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... Decreased Intake: • Low ... • Fatigue Chloride ... #Pathophysiology ... #Nephrology #Chloride
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... Differential Diagnosis Algorithm ... , TTKG, distal flow ... #IntercellularShift ... #Nephrology #Differential