8 results
Algorithm for Differentiating Gitelman syndrome from Bartter syndrome
 • Urine Chloride
 • Urine Ca/Cr ratio

Dr. Krithika
Algorithm for Differentiating ... Gitelman syndrome ... syndrome • Urine Chloride ... • Urine Ca/Cr ... #nephrology #hypokalemia
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
recessive salt-losing ... thiazide-sensitive sodium-chloride ... H+ secretion → Hypokalemia ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
- Differential ... Diagnosis Algorithm ... Bartter's syndrome, Gitelman's ... #differential # ... #causes #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
salt-losing tubulopathies ... thiazide-sensitive sodium chloride ... ratio 0.5%) Differential ... • Congenital chloride ... Syndrome #diagnosis #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... secreting tumor, Primary ... Bartter syndrome, Gitelman ... potassium #low #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... mEq/g suggests urinary ... Bartter syndrome, Gitelman ... #differential # ... potassium #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... Diagnosis Algorithm ... High Al, Low R - Primary ... Bartter's syndrome, Gitelman's ... #nephrology #causes
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis - Urinary ... Chloride Algorithm ... Bartter syndrome, Gitelman ... #Algorithm #nephrology ... #differential #