18 results
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ); nausea, vomiting ... of aspiration #Potassium ... #Binding #Hyperkalemia ... #pharmacology #table
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... Stimulation of Na/K-ATPase ... which imports K+ ... Diagnosis #Algorithm #causes ... #potassium #low
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Hypokalemia - Differential ... Differential #Diagnosis #Low ... #Potassium #Table ... #Classification ... #Causes
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... wasting from other causes ... suggests extra-renal causes ... consumption • Low ... #nephrology #low
Digoxin Pharmacology and Pathophysiology
1) Na/K ATPase Pump - Digoxin works by directly binding to and inhibiting
works by directly binding ... intracellular calcium causes ... - Hyperkalemia ( ... , in states of hypokalemia ... (or low potassium
Classification, Differential Diagnosis, and Features of Hyponatremia According to Volume Status 

Hypervolemic hypernatremia 
 - CHF
Classification, ... Glucocorticoid deficit - Hypokalemia ... deficit - Salt-losing ... Differential #Diagnosis #Table ... #Causes
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
aldosterone which does a lot ... sodium, which causes ... inhibiting drug classes ... this pathway, ending ... avoid harmful hyperkalemia
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
- Hypokalemia ... Differential #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
only if no clear cause ... Elimination (see Table ... acidosis) • Low ... Treatments: • K-Binding ... Management #Treatment #potassium
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 • Na+ channels open leading to a
efflux moving back ... Vaughan Williams Classification ... 3 - Potassium Channel ... #Pharmacology #Classification ... #Classes #pathophysiology