14 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... Insufficient blood ... #rheumatology # ... pharmacology #levels ... #lupus #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... -> AML: Blast crises ... #Leukemia #Hematology ... #Oncology #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... #comparison #table ... #rheumatology # ... diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Erythematosus #SLE ... #management #treatment
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... proteins on plts, leukocytes ... Causes purpura & ... #Transfusions #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Autoimmune diseases: SLE ... Drugs, Unknown cause ... #management #treatment ... #summary #rheumatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
proteins on plts, leukocytes ... Causes purpura & ... TRALI): Leading cause ... #Transfusion #diagnosis ... #management #hematology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Autoimmune (SLE ... Microbiology: Blood ... Septic Emboli Cause ... • Blood cultures ... #management #cardiology
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
are typically able ... treat the primary cause ... little coronary blood ... #diagnosis #algorithm ... #management #clinical
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
increasing coronary blood ... are typically able ... treat the primary cause ... little coronary blood ... #diagnosis #management