10 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... • Placenta • Leukocytes ... - Drugs - Pregnancy ... elevation DDX of Hepatic ... #hepatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Injury ... more specific for hepatic ... #Cholestatic #Transaminitis ... #diagnosis #differential ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Hepatopathy • Acute ... injury) • Ischemic ... ) • Non-hepatic ... #Diagnosis #hepatology ... #transaminitis
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
and hemorrhage Acute ... Pregnancy (AFLP) ... hepatitis #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... • Hepatic vein: ... melanoma, myeloma • Pregnancy
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
injury < 26 weeks ... replaced by non-hepatic ... #chemistry #diagnosis ... #differential # ... Hepatology #transaminitis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... ) Pathophysiology ... infiltration) Differential ... Pregnancy #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... Toxic: Medication, Pregnancy ... #Injury #Differential ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... PBC Labs: • Alkaline ... bile ducts Differential ... cholestasis of pregnancy ... malignancies, Hepatic
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Intravenous Drug Use • Pregnancy ... Syndrome, Ischemic Liver ... Vasculitis • Injury ... Venous #Arterial #pathophysiology ... #hematology #differential