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hematology differential classification management abnormal blood hemolytic product signs table agitation allergy atlas beaus clinical color cppd criticalcare delirium discoloration
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... proteins on plts, leukocytes ... Causes purpura & ... TRALI): Leading cause ... #diagnosis #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
proteins on plts, leukocytes ... Causes purpura & ... TRALI): Leading cause ... more likely to cause ... #diagnosis #management
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... prosthetic valve • Transfusion ... reactions ex. ... #Hemolytic #Anemia
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... reaction, Paroxysmal ... Extravascular #Causes ... #hematology #anemia
Differential Diagnosis - Noninfectious Causes of Fever CRITICAL DIAGNOSES: - Acute myocardial infarction - Pulmonary embolism or
Noninfectious Causes ... insufficiency - Transfusion ... reaction - Pulmonary ... Malignancy - Gout ... Noninfectious #Causes
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Allergen-specific lgE causes ... Examples: Acute transfusion ... recruitment of leucocytes ... classification #comparison
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
culture used to diagnose ... A reaction to phagocytosed ... Intracellular (leukocyte ... #Comparison #rheumatology ... #Diagnosis
Generalized Seizures and Pseudoseizures Generalized seizures "are conceptualized as originating as some point within, and rapidly engaging,
and metabolic causes ... sedative drugs, uremia ... to a conversion reaction ... Classification #Diagnosis ... Signs #Symptoms #Comparison
Causes Abnormal Urine Color - Differential Diagnosis Turbid White Urine (Albinuria): • Chyluria, Filariasis, Schistosomiasis, Malignancy, Phosphaturia,
Causes Abnormal ... - Differential Diagnosis ... deficiency, sickle cell anemia ... , thalassemia, transfusion ... reaction) • Chlorpromazine
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