33 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... lgE causes mast-cell ... reaction, Haemolytic ... recruitment of leucocytes ... hypersensitivity #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Reactions: • Immune ... Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... reaction: Usually
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
reaction • Type ... an immune reaction ... An allergic reaction ... #Allergic #Reactions ... Classification #Diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... common immune reaction ... Reaction (AHTR) ... • Allergic reaction
Eosinophils (Eos) and hypereosinophilia (HE)
Caused by eosinophilopoietic cytokines
Common causes:
 - Drug reaction
 - Helminth infection
 -
: - Drug reaction ... infection - Allergic ... reaction - Atopic ... + T cells) - Allergic ... #Differential #Diagnosis
Differential Diagnosis - Noninfectious Causes of Fever

CRITICAL DIAGNOSES:
 - Acute myocardial infarction
 - Pulmonary embolism or
Noninfectious Causes ... insufficiency - Transfusion ... reaction - Pulmonary ... - Transplant rejection ... Noninfectious #Causes
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... released during an allergic ... reaction or asthma ... Or Inflammatory Reactions ... #causes #hematology
Hemolysis Classification - Intrinsic and Extrinsic Causes

Commentary: Another way to think of immune hemolysis would be
and Extrinsic Causes ... hemolysis, hemolytic transfusion ... reactions) - Dr ... #Differential #Diagnosis ... #Causes #Algorithm
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Classification Diagnosis ... exposure • Non-allergic ... drug reaction - ... cell-mediated in > 90% of cases ... Classification #Types #Diagnosis