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differential management blood classification hemolytic product table anesthesia checklist extravascular hemolysis hypersensitivity hyperthermia intravascular perioperative taco trali transfusions types workup
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... lgE causes mast-cell ... reaction, Haemolytic ... recruitment of leucocytes ... hypersensitivity #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Reactions: • Immune ... Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... Reaction (AHTR) ... • Allergic reaction ... #hematology #reactions
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... reaction, Paroxysmal ... reaction • Intrinsic ... #hematology #anemia
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... prosthetic valve • Transfusion ... reactions ex. ... #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
maintained fever CAUSES ... device • Blood transfusion ... • Allergic reaction ... #Anesthesiology ... Anesthesia #Checklist #Diagnosis
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