10 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... lgE causes mast-cell ... reaction, Haemolytic ... hypersensitivity #reactions ... #types #allergy
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Types: • Leukocyte ... Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... #hematology #reactions
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... Reaction (AHTR) ... • Allergic reaction ... #hematology #reactions
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... - Red blood cell ... destruction after transfusion ... with mismatched blood ... #Diagnosis #Reactions
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Reactions TRALI ... of high parity blood ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... released during an allergic ... reaction or asthma ... Or Inflammatory Reactions ... #causes #hematology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Jaundice/Hemolytic reactions ... reaction - Tumor ... Failure • SLE • Type ... Blood transfusion ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Jaundice/Hemolytic reactions ... reaction - Tumor ... Failure • SLE • Type ... Blood transfusion ... #causes #potassium
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... are asthma, allergy ... , drug reaction, ... #Differential #diagnosis ... #hematology #eosinophilia
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
transfusion • ... Allergic reaction ... • Intracranial blood ... #Anesthesiology ... Anesthesia #Checklist #Diagnosis