14 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
reactions. ... lgE causes mast-cell ... reaction, Haemolytic ... recruitment of leucocytes ... #reactions #types
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
reaction • Type ... an immune reaction ... reaction • Type ... An allergic reaction ... Classification #Diagnosis
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Reactions: • Immune ... Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... reaction: Usually
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... common immune reaction ... Reaction (AHTR) ... • Allergic reaction
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
the total white blood ... released during an allergic ... reaction or asthma ... basophilic leukemia Hypersensitivity ... Or Inflammatory Reactions
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Reactions TRALI ... of high parity blood ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... - Red blood cell ... destruction after transfusion ... with mismatched blood ... #Diagnosis #Reactions
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... Jaundice/Hemolytic reactions ... reaction - Tumor ... Blood transfusion ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
- Differential Diagnosis ... Jaundice/Hemolytic reactions ... reaction - Tumor ... Blood transfusion ... #causes #potassium
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... for secondary causes ... are asthma, allergy ... , drug reaction, ... #Differential #diagnosis