10 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
reactions. ... lgE causes mast-cell ... reaction, Haemolytic ... recruitment of leucocytes ... #reactions #types
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
reaction • Type ... an immune reaction ... reaction • Type ... An allergic reaction ... Classification #Diagnosis
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Reactions: • Immune ... Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... reaction: Usually
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... common immune reaction ... Reaction (AHTR) ... • Allergic reaction
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... released during an allergic ... reaction or asthma ... basophilic leukemia Hypersensitivity ... Or Inflammatory Reactions
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Peri-operative Hyperthermia ... OF HYPERTHERMIA ... device • Blood transfusion ... • Allergic reaction ... Anesthesia #Checklist #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... Reactions TRALI ... without other cause ... #Reactions #hematology ... #diagnosis #comparison
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
Causes of Acute ... - Differential Diagnosis ... Iatrogenic: • Transfusion ... reaction • Malignant ... Hyperthermia
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... When the specific allergen ... destruction after transfusion ... sclerosis #Hypersensitivity ... #Diagnosis #Reactions
Hyperthermic Toxidromes
Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures.
 • Sympathomimetic -
Hyperthermic Toxidromes ... Ideosyncratic reaction ... pharmacogenetic disease caused ... #Toxidromes #comparison ... #table #diagnosis