17 results
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... Reaction (FNHTR ... Reaction (AHTR) ... Reaction (DHTR) ... proteins on plts, leukocytes
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Reactions Immune ... Reaction (FNHTR ... common immune reaction ... Reaction (AHTR) ... proteins on plts, leukocytes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Jaundice/Hemolytic reactions ... reaction - Tumor ... Blood transfusion ... #hyperkalemia #differential
Hemolysis Classification - Intrinsic and Extrinsic Causes

Commentary: Another way to think of immune hemolysis would be
hemolysis, hemolytic transfusion ... reactions) - Dr ... Intrinsic #Extrinsic #Differential
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
hypersensitivity reactions ... Examples: Acute transfusion ... reaction, Haemolytic ... recruitment of leucocytes ... hypersensitivity #reactions
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Jaundice/Hemolytic reactions ... reaction - Tumor ... Blood transfusion ... #hyperkalemia #differential
When assessing a patient with acute dyspnea during or shortly following a transfusion, it is challenging
shortly following a transfusion ... challenging to differentiate ... #Diagnosis #Transfusion ... #Reaction #TRALI
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
HUS) • Other: Transfusion ... reaction, Paroxysmal ... implicated) - Transfusion ... reaction • Intrinsic ... Extravascular #Causes #differential
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... AIHA, Cold AIHA, Transfusion ... reactions, Drug-associated ... #Hemolysis #Differential
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... prosthetic valve • Transfusion ... reactions ex. ... Hemolytic #Anemia #Differential