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erythematosus lupus als behcet calcium cerebritis chronic cll cns deposition fungal hemophagocytic hlh infections infectiousdiseases lateral leukemia lymphocytic lymphohistiocytosis macrophage
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
(ANA) - 95% - Initial ... Treatment: • ... #Summary #diagnosis ... #rheumatology # ... management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... #CNS #neurology ... #rheumatology # ... #management #treatment
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... Treatment: • Corticosteroids ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... →Activation of CD8 ... : SLE+++, Adult-onset ... #management #treatment ... #summary #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... skin injury) • Neurologic ... Arthritis, AS Treatment ... #diagnosis #management ... #rheumatology #
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pseudogout Summary ... (CPPD) Pathophysiology ... Crowned Dens Syndrome ... #Rheumatology # ... diagnosis #management
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Sclerosis (ALS) Summary ... lateral sclerosis Pathophysiology ... of the nervous system ... column Treatment ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... with no early symptoms ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
erythematosus (SLE ... cell lymphoma Pathophysiology ... the systemic symptoms ... Hypoalbuminemia Treatment ... #management #rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... : • Increased leukocyte ... Aspergillosis Pathophysiology ... the circulatory system ... #Management #Infections
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