14 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... #CNS #neurology ... #rheumatology # ... #management #treatment
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
(ANA) - 95% - Initial ... /systemic sclerosis ... #Summary #diagnosis ... #rheumatology # ... management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease ... skin injury) • Neurologic ... Arthritis, AS Treatment ... #diagnosis #management ... #rheumatology #
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Summary ALS: combination ... Pathophysiology ... of the nervous system ... #neurology #diagnosis ... #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
(CNS) dysfunction ... erythematosus [SLE ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
- Summary Multiple ... central nervous system ... Signs and symptoms ... #diagnosis #management ... #neurology #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Nephrogenic DI Hematologic ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
as SLE, atherosclerotic ... Symptoms (SX) in ... , particularly scleritis ... chorioretinitis, CNS ... #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphocytic Leukemia - Summary ... with no early symptoms ... cells can indicate disease ... microglobulin Treatment ... workup #oncology #hematology
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
erythematosus (SLE ... and the systemic ... symptoms Histopathological ... Hypoalbuminemia Treatment ... #management #rheumatology