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diagnosis management algorithm chronic cll differential lymphocytic anemia aplastic cbc classification dermatology erythematosus hemeonc hodgkins lupus lymphoma myelodysplasia myelodysplastic neutrophil
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... extramedullary disease ... - infiltrates (anemia ... lymphoid organs When Cancer ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... cells can indicate disease ... Lymphocytosis: Absolute blood ... diagnosis #workup #oncology ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
: Acute blood loss ... hemolysis, deficiency anemia ... Malignancy: Metastatic cancer ... Vasculitides, IBD, Celiac disease ... Matthew Ho, MD
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
of peripheral blood ... leukocytes. ... Tissue damage • Leukemia ... • Autoimmune diseases ... neutrophil #WBC #CBC #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... , breast CA - Hematologic ... cancer such as ... neutrophils in the blood ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic Leukemia ... • Most common leukemia ... chemotherapy for low-risk disease ... Lauren Banaszak, MD ... #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
myelodysplastic syndrome (MDS ... virus (EBV) • Leukemia ... Hypocellular/Hypoplastic MDS ... result from low blood ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... Myeloproliferative Disease ... Syndromes #diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Malignancy (e.g. hematologic ... • CBC, TSH and urinalysis ... Hodgkin lymphoma and leukemia ... • Lung cancer ... • Cervical cancer
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full Blood ... marrow biopsy - if blood ... number of sites of disease ... classification #hematology ... #oncology #management
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