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diagnosis rheumatology algorithm blood druginduced product reactions summary treatment activation acute causes comparison dermatology differential erythematosus hemophagocytic hlh lymphohistiocytosis macrophage
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... , SCLE-DIL (terbinafine ... • Immunologic Workup ... • Immunologic Workup ... of SLE • Evolution
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management ... versus DIL • ... • Immunologic Workup ... of SLE • Evolution ... #Summary #rheumatology
Algorithm for the Evaluation of Acute Diarrhea (< 7 days) Are the following present? 1.
Algorithm for the Evaluation ... Fecal leukocytes ... fever, abdominal ... #management #algorithm ... #workup #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Red Flags: • Fever ... fulminans - DIC ... Autoimmune Vasculitis (lupus ... deficiency Work ... coagulation studies • Urinalysis
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
, SCLE-DIL (terbinafine ... • Immunologic Workup ... • Evolution: ... #DIL #rheumatology ... diagnosis #treatment #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... erythematosus [SLE ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
• Clinical: fever ... Fibrinogen level, ↑ sIL ... Autoimmune diseases: SLE ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Product Types: • Leukocyte ... pain, dark urine, DIC ... cutaneous eruptions, diarrhea ... Transfusions #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
pain, dark urine, DIC ... proteins on plts, leukocytes ... cutaneous eruptions, diarrhea ... Transfusion #diagnosis #management ... #hematology #reactions
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
- Anasarca - Fever ... including systemic lupus ... erythematosus (SLE ... TAFRO #diagnosis #management ... #rheumatology #
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