14 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
and Nephrotic Syndromes ... hematuria. ... RBC casts in urine ... Proteinuria often ... but in severe cases
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient has hematuria ... and/or proteinuria ... have glomerular hematuria ... (RBC casts or dysmorphic ... RBCs in urine)?
Differentiation Between Nephrotic Syndrome and Nephritic Syndrome 
== Nephrotic Syndrome ==
Onset - Insidious 
Edema - ++++
Blood
- Normal/low Proteinuria ... - ++++ Hematuria ... cell casts - Absent ... - ++ Hematuria ... cell casts - Present
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
• 1ml blood/liter ... syndrome: • ... : - RBC casts ... - Proteinuria ... #blood
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... glomerular bleeding (proteinuria ... , RBC casts, dysmorphic ... Nephrology if cause ... Workup #urology #blood
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
proteins, documenting proteinuria ... • Ketones • Leukocyte ... • Urinary casts ... #urine #UNa #casts ... #glucosuria #hematuria
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Algorithm Red blood ... cells on urine ... RBCs and/or RBC casts ... nephrotic range) proteinuria
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... content [85].2>5 red blood ... cell/white cell casts ... Nephrocalcinosis causes ... Hematuria may be
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
, hematuria) • ... Goodpasture's cause ... reveals increasing blood ... , RBC casts, low ... differential #diagnosis #management
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
vast majority of cases ... Measure urine osmolality ... the underlying cause ... demyelination syndrome ... Diagnosis #Treatment #management