10 results
Utilization of Antibiotics as Antidotes

Valproic Acid Toxicity:
Carbapenems 

Amatoxin Mushrooms: 
Polymyxin B, Penicillin, Cyclosporine

Infographic by Mike O'Brien
@MikeEMPharmD

#Antibiotics
Antibiotics as Antidotes ... Valproic Acid Toxicity ... #Antibiotics #Antidotes ... #Toxicology #Pharmacology
Alkalinization shifts equilibrium toward the plasma and urine and away from the tissues.

#Management #Toxicology #Salicylate #Aspirin
the plasma and urine ... #Management #Toxicology ... Salicylate #Aspirin #Toxicity
Toxic Alcohol Ingestion
Alcoholic ketoacidosis - Methanol - Ethylene glycol - Isopropyl Alcohol
 • Metabolic Acidosis
 •
Gap • Serum / Urine ... Ingestion #diagnosis #toxicology ... #comparison #table
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
Salicylate Toxicity ... Resuscitation 2) Urine ... Salicylate #Aspirin #Toxicity ... #Toxicology #diagnosis
Toxidromes Compared: Anticholinergic, Cholinergic, Opioid, Sympathomimetic, Sedative-Hypnotic

During your physical exam, look for evidence of some of
acute cholinergic toxicity ... Opioid toxicity ... #Diagnosis #Toxicology ... #Toxidromes #Comparison
Toluene Poisoning - Diagnosis and Management Summary
What is it?  Volatile hydrocarbon, Glue or paint-sniffing, Occupational
lipid-soluble, Toxicity ... nephrocalcinosis) • Urine ... Toluene #Poisoning #Toxicology
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
Ketones in serum or urine ... Euglycemic #DKA #EDKA #Toxicity ... #Toxicology
Salicylate Poisoning - Toxicology

Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Salicylate Poisoning - Toxicology ... Acute toxicity ... Chronic toxicity ... Decontamination Urine ... #Toxicology #Pharmacology
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... thymidylate and purine ... evidence of marrow toxicity ... Methotrexate #Leucovorin #Antidote ... #Toxicology #Toxicity
Toxic Alcohol Ingestion: Clinical Features, Diagnosis, and Management
Methanol intoxication:
 • Accidental or intentional ingestion of adulterated
oxalate crystals in urine ... Ingestion #diagnosis #toxicology ... #comparison #table